Metoclopramide, Azithromycin, or Nondrug Pretreatment for UGIB to Reduce Second Endoscopy

Exclusion Criteria

• •1\. Known anaphylactic allergic reaction to erythromycin, azithromycin, and/or metoclopramide;
• •2\. Concurrent use of certain medications associated with tardive dyskinesia (TD):
• •a. Fluphenazine,
• •b. Haloperidol,
• •c. Loxapine,
• •d. Paliperidone,
• •e. Perphenazine,
• •f. Pimozide,
• •g. Risperidone,
• •h. Thiothixene,
• •i. Trifluoperazine;
• •3\. Concurrent use of certain medications associated with torsade de pointes:
• •a. Amiodarone,
• •b. Chlorpromazine,
• •c. Disopyramide,
• •d. Dofetilide,
• •e. Methadone,
• •f. Procainamide,
• •g. Quinidine,
• •h. Sotalol;
• •4\. Known history of TD, ventricular arrhythmias , or long QT syndrome;
• •5\. Already received erythromycin and/or azithromycin within the past 10 days, or metoclopramide within the past 4 days for other indications;
• •6\. Recipient of hematopoietic stem cell transplant;
• •7\. History of Neisseria gonorrhoeae infection;
• •8\. Pregnancy;
• •9\. Prior gastrectomy.