Age

25–65

Sex

FEMALE

Healthy volunteers

Not accepted

history of adverse reactions to any prior botulinum toxin treatments
history of vaccination or non-response to any prior botulinum toxin treatments
botulinum toxin treatment in the prior 6 months
present or history of neuromuscular disease, eyelid ptosis, muscle weakness, paralysis, or "dry eye"
history of peri-ocular surgery, brow lift or related procedures
procedures affecting the lateral canthal region in the prior 12 months
application of topical prescription medication to the treatment area
female subjects who are pregnant or are nursing a child

ET-01 in Subjects With Lateral Canthal Lines, LCL-208