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Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation | Clinical Trials | Clareo Health

TERMINATEDPHASE1/PHASE2

Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation

NCT03837665•University of Kansas Medical Center

View on ClinicalTrials.gov

Summary

By doing this study, researchers hope to find out if platelet rich plasma (PRP) can heal holes in the eardrum as an alternative to surgery.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients who meet criteria for tympanoplasty procedure
•Willing to comply with the protocol and attend all study visits
•Able to provide written informed consent

Exclusion Criteria

•Patients who have previously undergone middle ear or lateral skull base surgery
•Patients who would not qualify for a tympanoplasty
•Any type of platelet disorder, cancer, or ongoing systemic infection
•Any type of hemodynamic instability, septicemia, infection, tobacco use, any use of steroids to the ear drums
•Type I diabetes or other autoimmune pathology

Locations (1)

University of Kansas Medical Center

Kansas City, Kansas, United States

Key Dates

Start Date

May 2, 2018

Primary Completion Date

October 29, 2019

Completion Date

October 29, 2019

Last Updated

July 16, 2024

Enrollment

ACTUAL participants

Conditions

Tympanic Membrane Perforation

Interventions

Platelet Rich Plasma

BIOLOGICAL

Perf-Fix Study for Chronic Tympanic Membrane Repair

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Tympanic Membrane Perforation

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COMPLETED

Tympanoseal (Tympanic Membrane Device) Clinical Study

NCT02918942

Tympanic Membrane Perforation

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Wide Frequency Band Test of Hearing in Veterans

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Hearing Loss, Sensorineural

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 16, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation

Inclusion Criteria

Exclusion Criteria

Perf-Fix Study for Chronic Tympanic Membrane Repair

Tympanoseal (Tympanic Membrane Device) Clinical Study

Wide Frequency Band Test of Hearing in Veterans

Repair of Tympanic Membrane Perforation Using Tachosil Under Local Anesthesia

Eustachian Tube Function and Myringoplasty/Tympanoplasty