Breast Cancer Screening With Diffusion-weighted MRI in Women at High Risk for Breast Cancer

* Mammography, breast US, contrast-enhanced MRI, and DWI will be performed on the same day or within 1 month at baseline and then after 1 year, and images will be interpreted independently according to the Breast Imaging Reporting and Data System (BI-RADS) by experienced radiologists. * Each eligible woman, who provides informed consent for this study, will undergo mammography, breast US, contrast-enhanced MRI, and DWI at a 3T MR scanner. * Contrast-enhanced breast MRI will be performed before and after a gadolinium-based contrast agent injection. * Before contrast injection, DWI with b-value of 0, 800 and 1200 s/mm2 will be performed and will transfer into the server. * A total of 890 high-risk women for breast cancer will be enrolled in this study. * The BI-RADS 3 or higher is defined as test-positive. The reference standard will be a biopsy or at least 1 year of follow-up.