Thrombin Generation as a New Test for Anticoagulation Management in Patients With ECMO

Exclusion Criteria

• •Patient on veno-arterial ECMO after cardiac, cardiopulmonary surgery or after insertion of a left or biventricular cardiac assist device
• •Contraindication to curative anticoagulation
• •Congenital hemostasis disorder or anatomical abnormality predisposing to hemorrhage (hemophilia, constitutional thrombocytopathies, Willebrand disease, hereditary hemorrhagic telangiectasia, etc.)
• •History of heparin-induced thrombocytopenia
• •Moribund patient at the day of inclusion
• •Do Not Resuscitate decision
• •Subject under the protection of justice
• •Subject under guardianship or curatorship
• •Pregnancy
• •Breastfeeding