Lead Sponsor

Cancer Research Antwerp

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Histologically confirmed malignancy.
•Pain score ≥ 2 on a scale from 0 to 10.
•Radiological or (bone) scintigraphic evidence of bone metastasis at the site of pain.
•Lesions ≤ 5cm in largest diameter.
•Per lesion no more than 3 consecutive spine segments involved with one unaffected vertebral body above and below.
•No more than 3 painful lesions needing treatment.
•Life expectancy estimated at \> 3 months.
•Patients who have received the information sheet and signed the informed consent form.
•Patients must be willing to comply with scheduled visits, treatment plan, and other study procedures.
•Patients with a public and/or private health insurance coverage.

•Myeloma.
•Bone metastasis in previously irradiated sites.
•Previous radioisotope treatment for bone metastases.
•Complicated bone metastasis, i.e. impending and/or existing pathological fracture, spinal cord compression or cauda equina compression \[16\].
•Patients with significantly altered mental status or with psychological, familial, sociological or geographical condition potential hampering compliance with the study.
•Individual deprived of liberty or placed under guardianship.