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Dichoptic Video Treatment for Amblyopia in Children Age 3-7 Years
1. To determine whether watching contrast-rebalanced dichoptic videos is effective in improving visual acuity and reducing interocular suppression in amblyopic children 2. To compare the amount of visual acuity improvement achieved with the videos to tha amount achieved with patching (standard treatment for amblyopia)
Contrast-rebalanced binocular iPad tablet games (with fellow eye contrast reduced) have been shown to be an effective treatment for amblyopia. However, the games can be challenging for some of the youngest children and boring for some of the older children with amblyopia. To provide additional treatment options using the same contrast-rebalancing approach, we have processed animated videos to allow dichoptic viewing, with full contrast for the amblyopic eye and reduced contrast for the fellow eye. Children will be randomly assigned to watch dichoptic videos (experimental treatment) or patch 2 hours/day every day(standard-of-care amblyopia treatment) for 2 weeks. At the 2-week primary outcome visit, children in the patching group will cross over to the videos and return for a secondary outcome visit at 4 weeks. Families will have the option to continue with the vdeos for up to 8 weeks.
Age
3 - 7 years
Sex
ALL
Healthy Volunteers
No
Eileen E Birch
Dallas, Texas, United States
Start Date
January 31, 2019
Primary Completion Date
July 6, 2021
Completion Date
August 31, 2021
Last Updated
January 24, 2025
65
ACTUAL participants
patching
OTHER
Dichoptic videos
OTHER
Lead Sponsor
Retina Foundation of the Southwest
NCT07417046
NCT04378790
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06380517