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The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters | Clinical Trials | Clareo Health

COMPLETEDNA

The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters: Randomised Double-blind Placebo-controlled Study

NCT03811756•VIST - Faculty of Applied Sciences

View on ClinicalTrials.gov

Summary

Placebo controlled double-blind multi-dose comparative study of the effects of coenzyme Q10 and collagen formulation with improved water-solubility in healthy adults. One group (test group) will receive investigational product - test syrup (daily dose 10 mL: fish collagen: 4000 mg, water soluble CoQ10 (Q10Vital®): 50 mg, vitamin C: 80 mg, vitamin A: 920 μg, biotin: 150 μg) and the other (placebo group) placebo syrup without those active ingredients. Participants will test continuous administration of placebo or investigational product for 12 weeks in order to demonstrate and assess multiple-dose effects on skin condition and signs of skin aging.

Eligibility

Age

40 - 65 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Caucasian female volunteers aged between 40 and 65 years at the time of the signature of Informed consent form (ICF),
•Signed Informed consent form (ICF),
•Fitzpatrick skin phototypes II and III,
•Signs of skin aging,
•In good health condition,
•Willingness to avoid a consumption of any food supplements containing CoQ10 and other antioxidants, collagen or vitamins during the study,
•Willingness to follow all study procedures and keeping a diary during the study (to follow their compliance and palatability).

Exclusion Criteria

•Pregnancy or breastfeeding,
•Known or suspected allergy to any ingredient of the tested products,
•Changes in dietary habits and dietary supplementation in last three months prior to inclusion,
•Regular use of food supplements containing CoQ10 or other antioxidants, collagen or other protein-based food supplements, vitamin A, vitamin E or biotin in last three months prior to inclusion,
•Veganism,
•Changes in cosmetic facial and body care routine in last month prior to inclusion,
•Diagnosed and uncontrolled/untreated/unregulated disease,
•Any clinically significant history of serious metabolic disease, digestive tract disease, liver disease, kidney disease, haematological disease,
•Acute skin diseases,
•Skin pigmentation disorders,
+5 more criteria

Locations (1)

Higher School of Applied Sciences, Institute of Cosmetics

Ljubljana, Slovenia

Key Dates

Start Date

October 15, 2018

Primary Completion Date

February 19, 2019

Completion Date

July 10, 2019

Last Updated

October 14, 2021

Enrollment

ACTUAL participants

Conditions

Dermis DensityTrans Epidermal Water Loss (TEWL)Skin HydrationWrinklesDermis Thickness

Interventions

Test syrup containing CoQ10 and collagen

DIETARY_SUPPLEMENT

Placebo syrup

DIETARY_SUPPLEMENT

Efficacy and Safety of PN20 (Plinest) for the Improvement of Skin Hydration

NCT06821854

Skin HydrationSkin Elasticity

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COMPLETEDNA

The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

NCT04988412

Dermis DensityWrinkles+5 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 14, 2021Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Inclusion Criteria

Exclusion Criteria

Efficacy and Safety of PN20 (Plinest) for the Improvement of Skin Hydration

The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health