The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Exclusion Criteria

• •Pregnancy or breastfeeding,
• •Known or suspected allergy to any ingredient of the tested products,
• •Changes in dietary habits and dietary supplementation in last three months prior to inclusion,
• •Regular use of food supplements containing CoQ10 or other antioxidants, collagen or other protein-based food supplements, vitamin A, vitamin E or biotin in last three months prior to inclusion,
• •Veganism,
• •Changes in cosmetic facial and body care routine in last month prior to inclusion,
• •Diagnosed and uncontrolled/untreated/unregulated disease,
• •Any clinically significant history of serious metabolic disease, digestive tract disease, liver disease, kidney disease, haematological disease,
• •Acute skin diseases,
• •Skin pigmentation disorders,
• •Increased cholesterol and use of cholesterol lowering drugs (statins),
• •Anticipated sunbathing or solarium visits before or during the study,
• •Invasive rejuvenation treatments (e.g. needle rollers, needle mesotherapy, deep/medium-deep chemical peels etc.) in last 6 months prior to study entry,
• •Non-invasive rejuvenation treatments (e.g. radiofrequency, electrotherapy, ultrasound therapy) in last 2 months prior to study entry,
• •Mental incapacity that precludes adequate understanding or cooperation.