Men with a personal history of prostate cancer

Unaffected males who are at higher risk for prostate cancer (family history of prostate cancer or African American males)

Men who previously tested positive for a mutation may be eligible for Specific Aims 2-7

Men with a known familial mutation

Men who previously participated in the Genetic Evaluation of Men (GEM) study (IRB#14S.546) will be offered participation in EMPOWeR -

Evaluation and Management for Prostate Oncology, Wellness, and Risk (EMPOWeR)