an observational cross-sectional study is done to calculate the electrolyte imbalance at different stages of chronic kidney disease at tertiary care hospitals of south Punjab, Pakistan .The outcomes of chronic kidney disease and end stage of renal failure will be calculated according to standard protocol. Under the supervision of pathologists, pharmacologists, pharmacists, nephrologists, urologists and biostatistician. The standard protocol was authorized by ethical committee of each center. patient consent form was
