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Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs. Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.
Age
18 - 90 years
Sex
ALL
Healthy Volunteers
No
Urology Department Fondazione IRCCS Policlinico San Matteo
Pavia, Italy
Start Date
January 1, 2010
Primary Completion Date
December 20, 2018
Completion Date
December 25, 2018
Last Updated
December 31, 2018
500
ACTUAL participants
systematic review
OTHER
Lead Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT07371507