1. Hong Kong Citizen who is able to speak Cantonese and read Chinese;
2. Aged ≥ 18 years;
3. Presence of the DSM-IV diagnostic criteria of MDD based on Chinese-bilingual Structured Clinical Interview for DSM-IV (SCID);
4. Score on PHQ-9 is 10 or above;
5. More than 1 sleep or circadian problem according to the Sleep and Circadian Problem Checklist, including time needed to fall asleep more than 30 minutes for more than 3 nights per week, less than 6 hours of sleep per night or at least 9 hour of sleep per night per 24 hour period for at least 3 nights per week, variability in the sleep-wake schedule at least 2.78 hours within a week, and falling asleep after 2 am on at least 3 nights per week;
6. Adequate opportunity and circumstances for sleep to occur; and
7. Willing to give informed consent and comply with the trial protocol.
You may not be if
1. Presence of other psychiatric disorders as defined by the DSM-IV diagnostic criteria using SCID;
2. Major medical or neurocognitive disorders that make participation infeasible;
3. Have suicidal ideation based on Beck Depression Inventory (BDI-II) Item 9 score ≥ 2;
4. Untreated sleep disorders based on SLEEP-50 (≥ 7 on narcolepsy; ≥ 15 on OSA; ≥ 7 on RLS/PLMD);
5. Past or current involvement in a psychological treatment programme for depression and/or sleep problems;
6. Shift work, pregnancy, work, family, or other commitments that interfere with regular night-time sleep patterns;
7. Hospitalization; and
8. A change in psychotropic drugs within 2 weeks before baseline assessment
Clareo Health | A Transdiagnostic Sleep and Circadian Treatment for Major Depressive Disorder
