Patients undergoing a septorhinoplasty (septoplasty permissible if patient will also undergo sinus surgery)

Doyle splints to be used

Alcohol or opioid use disorder

History of chronic pain disorders

Regular use of acetaminophen/NSAIDS (\>4x per week)

Patients who use narcotics or neuromodulating drugs (e.g. gabapentin, nortriptyline)more than 2x per week on average.

Gastrointestinal ulcers or bleeding

Chronic kidney disease/known decreased renal function (estimated glomerular filtration rate \<60)

Liver cirrhosis or other hepatic impairment

Prior adverse reaction to opioids or NSAIDS

Other contraindications to any drug classes in either group.

Pain Control Following Sinus Surgery