Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Bordeaux
With
Genzyme, a Sanofi Company
Age
18–60
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
PATIENTS
Male or female
Age 18-60 years
RRMS diagnosis according to McDonald criteria (Polman et al., 2005);
Treated with Aubagio® (Indication for first line therapy)
Native French speaking
Being affiliated to health insurance
Having signed an informed consent (at the latest on the day of inclusion and before any examination required by research)
HEALTHY CONTROLS
Male or Female,
Age 18-60 years
Willing to participate and to sign informed consent.
Being affiliated to health insurance
Having signed an informed consent (at the latest on the day of inclusion and before any examination required by research)
You may not be if
PATIENTS
History of neurological disease and/or other neurological diseases,
Psychiatric comorbidity including severe depression according to DSM-IV,
Alcohol or other addiction to toxic,
Disabling visual or motor problems preventing participation to neuropsychological assessments,
Acquisition disorders : Dyslexia, Dysphasia, Dyscalculia and dyspraxia,
Dosage change, stop or start of hypnotic or anxiolytic or antidepressive treatment less than 30 days
Relapse since less than one month,
Steroid treatment less than one month (be taken orally or by infusion) at the dosage of 500mg daily,
Prior neuropsychological testing with the same tests less than 6 months
Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI
Illiteracy, is unable to count or to read
Pregnant or breastfeeding women
Patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)
HEALTHY CONTROLS
History of neurological disease and/or neurological diseases
Psychiatric comorbidity including severe depression according to DSM-IV;
Alcohol or other toxic addiction;
Known cognitive complaint or neuropsychological affection
Hypnotic or anxiolytic or antidepressive treatment,
Prior neuropsychological testing with the same tests less than 6 months
Acquisition disorders: Dyslexia, Dysphasia, Dyscalculia and dyspraxia,
Steroid treatment less than one month (be taken orally or by infusion) at the dosage of 500mg daily,
Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI
Illiteracy, is unable to count or to read
Pregnant or breastfeeding women
Person concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)
Clareo Health | Cognition and MRI Markers in MS Patients With Aubagio® Treatment
