Jared Younger, PhD

CONTACT

Lead Sponsor

University of Alabama at Birmingham

Collaborators

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

•1. 18 to 65 years of age
•2. Healthy volunteer OR Clinical diagnosis of Multiple Sclerosis (MS) OR Meets 2016 American College of Rheumatology (ACR) case definition criteria for fibromyalgia OR Meets 1994 Fukuda case definition criteria for Chronic Fatigue Syndrome

•1. Contraindication to MRI
•2. Pregnancy
•3. Lactation
•4. Individuals who are unable to participate in the imaging portion due to severity of their medical condition
•5. Chronic infectious disease (e.g. HIV, HCV)
•6. Viral or bacterial illness requiring medical attention and/or antibiotics within 1 month of study participation
•7. Diagnosis of cancer, including leukemia
•8. Blood or blood clotting disorder
•9. Except for individuals with MS, a diagnosis of autoimmune disease is exclusionary
•10. Positive urine β-hCG test day of procedure or a serum -hCG test within 48 hours prior to the administration of \[18F\]DPA-714
•11. Currently enrolled in a clinical trial utilizing experimental therapies