Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Eli Lilly and Company
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
All: Must have a body mass index of 18.0 to 32.0 kilograms per square meter (kg/m²), inclusive, for Parts A and B, and 18.0 to 45.0 kg/m², inclusive, for Part C and a minimum body weight of 50 kilograms
For PART A and B only, regarding the inclusion of healthy Japanese participants: Minimum age is 20 years and the participant's biological parents and all of the participant's biological grandparents must be of exclusive Japanese descent and must have been born in Japan
AD:
* Must have a diagnosis of AD for at least 12 months with either poor response to topical treatments or inability to use topical treatments
* Must agree to use moisturizer daily throughout the treatment period
You may not be if
All: must not have previously completed a clinical trial with a molecule targeting interleukin-33 (IL-33) or its receptor
AD:
* Must not have received certain topical medications for AD within 2 weeks prior to randomization
* Must not have received certain oral medications for AD or received phototherapy within 4 weeks prior to randomization
* Must not have received any antibody-based biologic agents (marketed or investigational) within 5 half lives (t1/2) of the drug prior to randomization
* Must not have received intravenous, intramuscular, or intra-articular steroids in the past 6 weeks prior to randomization
Clareo Health | A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis
