1. Previous PSA test or prostate MRI within the prior two years of screening/consent visit

2. Evidence of a urinary tract infection or history of acute prostatitis within the last 6 months

3. Previous history of prostate cancer, prostate biopsy or treatment for prostate cancer

4. Any potential contraindication to MRI

5. Any potential contraindication to prostate biopsy

6. Dementia or altered mental status that would prohibit the understanding or rendering of informed consent.

7. Any other medical condition precluding procedures described in the protocol

Prostate Cancer Screening Trial Using Imaging