Discovery of Novel Biomarkers of Dietary Exposure in the EPIC Calibration Study

Subjects participating in the study are characterized by the availability of one 24-hr urine sample, blood serum, 24-hr dietary recall (24HDR) and food frequency questionnaire (FFQ) data. The main objectives of the proposal are: 1. To collect a set of high-quality metabolomic data containing rich information on the food-derived metabolome. 2. To mine this data in different Metabolome-Wide Association Studies in order to identify food-derived metabolites discriminating consumers and non-consumers of various foods, nutrients and dietary patterns. 3. To identify the food-derived metabolites characteristic of the consumption of the different foods/nutrients and dietary patterns.