Effectiveness and Safety of Collagen Complex COLLOST in Anti-age Therapy

This study evaluates the statistics of anti-age treatment in outpatient sites in Russia (involution indicators: clinical scales; instrumental diagnostics, ultrasonic scannings, assesment of allergic state, efficacy assesment in according with GAIS scale) in routine clinical practice with focus on collagen therapy.

This non-interventional study covers 60 patients (females with involuntary changes of the face skin) from Russian sites. The following data will be collected and analyzed after the end of treatment: * demography * assessment of allergic state * safety data * severity of aging effect * clinical scales results before 1visit and after end of treatment * GAIS effectiveness assessment * instrumental diagnostic before 1visit and after end of treatment * hydration * elasticity * microcirculation level * lipofuscin level * ultrasound scanning * derma echo density