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COMPLETEDPHASE4

Reducing Hemarthrosis in ACL Reconstruction With BTB Autograft by the Administration of Intravenous TXA

Reducing Hemarthrosis in Anterior Cruciate Ligament Reconstruction With BTB Autograft by the Administration of Intravenous Tranexamic Acid: A Double-Blind Randomized Control Study

NCT03631355•NYU Langone Health

View on ClinicalTrials.gov

Summary

Detailed Description

The purpose of the proposed study is to evaluate the effects of administering intravenous tranexamic acid (TXA) to patients undergoing anterior cruciate ligament (ACL) reconstruction with bone-patellar tendon-bone autograft to minimize hemarthrosis within the knee joint and post operative pain. Patients received the standard arthroscopic ACL reconstruction with a BTB autograft and were randomized to either receiving or not receiving two individual doses of TXA intra-operatively or receive. The goal of the study is to determine and evaluate the effect of intra-operative TXA on post-operative hemarthrosis, pain reduction, and opioid consumption.

Eligibility

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•PATIENTS UNDERGOING AN ACL RECONSTRUCTION WITH BTB AUTOGRAFT

Exclusion Criteria

•Legally incompetent or mentally impaired (e.g., minors, Alzheimer's subjects, dementia, etc.)
•Younger than 18 years of age
•Any patient considered a vulnerable subject
•Have bleeding or clotting disorder
•Preoperative anticoagulation therapy
•Abnormal coagulation profile
•Renal disorder or insufficiency
•Sickle cell disease

Locations (1)

New York University School of Medicine

New York, New York, United States

Key Dates

Start Date

June 6, 2018

Primary Completion Date

March 1, 2020

Completion Date

March 1, 2020

Last Updated

February 24, 2021

Enrollment

110

ACTUAL participants

Conditions

Anterior Cruciate Ligament Reconstruction

Interventions

Tranexamic Acid

DRUG

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RECRUITINGNA

Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 24, 2021Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Reducing Hemarthrosis in ACL Reconstruction With BTB Autograft by the Administration of Intravenous TXA

Inclusion Criteria

Exclusion Criteria

Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy

Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.

Effects of tDCS on Motor Cortex During ACL Recovery

Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

Graft Maturity After Blood Flow Restriction Training in ACL Reconstruction