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Study of the Physiology of Pre-eclampsia and Vascular Intrauterine Growth Restriction With Constitution of a Biological Collection
Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
No
CHi Creteil
Créteil, France
Start Date
August 6, 2018
Primary Completion Date
August 1, 2023
Completion Date
April 1, 2024
Last Updated
December 21, 2022
500
ESTIMATED participants
collect of placenta, blood and urinary samples at delivery
OTHER
Lead Sponsor
Centre Hospitalier Intercommunal Creteil
NCT06408181
NCT06821685
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT04520048