Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre for Addiction and Mental Health
Age
18–55
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
ages 18-55
meet DSM-5 diagnostic criteria for cannabis use disorder (cannabis use \>1 g/day, CUDIT score \>12)
meet DSM-5 diagnostic criteria for Major Depressive Disorder as determined using the SCID
be an outpatient receiving a stable dose of antidepressant medication(s) for at least 1 month
have a Hamilton Depression Rating Scale (HDRS-17) baseline total score greater than 14
have a Full Scale IQ greater than 80 as determined by the WTAR
be a non-treatment seeking cannabis user
evidence of sufficient motivation and effort as measure by a Test of Memory Malingering (TOMM) score greater than 45
urinary baseline THC-COOH levels greater than 150 ng/ml
You may not be if
meets criteria for abuse or dependence of alcohol or other illicit substances within the part 6 months (with the exception of cannabis, nicotine, or caffeine)
positive urine screen for illicit substances other than cannabis, nicotine or caffeine
current suicidal or homicidal ideation
psychotic disorder diagnosis (e.g. schizoaffective disorder, major depression with psychotic features) as determined by the SCID
head injury with loss of consciousness greater than 2 minutes or requiring hospitalization
neurological or medical condition determined to effect cognition
be treatment seeking for cannabis use
Clareo Health | Effects of Cannabis Abstinence on Symptoms and Cognition in Depression
