Patients will answer the following the questationnaire:
Name age gender
1 Socio echonomic status (average salary \\year) (Education) (Job) (residence)
1. Body mass index (height\\wt2)
2. Disease duration in months.
3. Smoking (yes) (No) Passive smoker Ex smoker
4. Reproductive history:
* age of menarche….
* menstrual cycle….. regular or not……. P / C
* How many pregnancies…….. living.
* Abortion.
* patient age at first birth (….).
* breast feeding…..(yes)…….(no)
* use of contraceptives (yes)…pills injections IUD (N0)……
* Does patient get pregnant during disease?...(Yes)……(no)….. Does the arthritis improved (…)or got worse (…..) -flared during the purpurium.(yes) … (No)
* age of menupause…. 10 Exposure to sun….(yes)…..(No) 11 -Theraputic history… (Newly diagnosed)
* (Previously diagnosed),
* Does the patient receiving ttt? (yes) (Steroid)……. (NSAIDS)……. (2nd line drugs) (.Methotrexat(.…), Leflonamide (….) Hydroquine(….) (NO)……..
* The study will include 100 patients fullfilling ACR 2010
* Patients well subjected to
* Through clinical examination with emphysis on joints examination
* venous blood sampling will withdrawn and the following investigations will be done.
* Serum VIT D level
* Serum calcium and phosphorus
* Anti cyclic citrullinated peptide.
* ESR
