Recent diabetic ketoacidosis or hyperosmolar hyperglycemia
Other causes of diabetes other than T2D
For participants undergoing the optional Parts 2-4 of visits 2 and 4, diuretics, sodium-glucose co-transport (SGLT) 2 or 1 blockers, daily NSAIDs or aspirin, sulfonamides, procaine, thiazolsulfone or probenecid, atypical antipsychotics or regular use of oral steroids
Evidence of bleeding disorder or complications from bleeding
Use of aspirin, NSAIDS or other blood thinner that cannot be safely stopped for a sufficient time period before and after the biopsy so as to add no additional risk of bleeding
Blood urea nitrogen (BUN) \> 80 gm/dL
INR \> 1.4
PTT \> 35 seconds
Hemoglobin (Hgb) \< 10 mg/dL
Platelet count \< 100,000 / µL
Uncontrolled or difficult to control hypertension (\> 150/90 mmHg at the day of biopsy)
eGFR \< 40 mL/min/1.73m2
Single kidney (either by history, documented by prior imaging or ultrasound performed prior to the biopsy)
\> 2 cm discrepancy between left and right kidney sizes based on largest longitudinal diameter determined by ultrasound performed prior to the biopsy.
Kidney size: One or both kidneys \< 9 cm
Hydronephrosis or other important renal ultrasound findings such as significant stone disease
Any evidence of a current urinary tract infection as indicated on day of biopsy
