Application of Circulating Tumor DNA Test in the Diagnosis and Treatment of Patients With Advanced Rectal Cancer

Inclusion Criteria

• •Histologically or cytologically confirmed primary rectal cancer；
• •First treatment；
• •18 years of age or older, male or female；
• •According to the indications of operation, surgical treatment can be carried out；
• •According to the indications of radiotherapy, radiotherapy can be carried out；
• •The physical status score of ECOG was 0\~1；
• •Organ function is appropriate;
• •Expected survival time more than 3 months；
• •During the treatment period and 6 months after treatment, contraception was not in lactation；
• •The patient volunteered and signed the informed consent.