Diagnosis of ulcerative colitis diagnosed at least 6 months earlier
Moderate or severe activity defined by a Mayo score
No serious infection, chronic diseases, diabetes and tuberculosis
Unefficient by using 5-ASA, glucocorticoid or azathioprine
Written informed consents were obtained from all subjects
Capable of good communication with researchers and follow the entire test requirements
Negative pregnancy test for women of childbearing potential (from menarche to menopause)
You may not be if
Pregnant or breastfeeding women or cognitively impaired adults
History of malignant disease
Infectious colitis
Patients with known allergies to culture medium
Patients having participated in clinical trials with any investigational drug within 1 month prior to enrolment in this study
Patients with suspicion of Crohn's enterocolitis, indeterminate colitis, ischaemic colitis, radiation colitis, diverticular disease associated colitis, or microscopic colitis
Patients with previous colectomy
Positive to one or more of the infectious disease panel
Treatment with surgery or biological treatment (infliximab or adamizumab) or Cyclosporine or tacrolimus or mycophenolate in the 8 weeks prior to inclusion in the study
Presence of severe concomitant diseases
Patients with clostridium difficult or cytomegalovirus infection
Clareo Health | Adipose Mesenchymal Stem Cells (AMSC) for Treatment of Ulcerative Colitis