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Keep this study
Lead
PolyActiva Pty Ltd
Participants who are currently managing their Open Angle Glaucoma with combination drop therapy will be recruited. Drop therapy will cease in the treatment eye and continue in the contralateral eye. The treated eye will receive via injection, a single PA5108 ocular implant. Participants will be monitored for safety and tolerability of the ocular implant until it completely biodegrades.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Grade 3 or 4 open angle glaucoma (Shaffer-Etienne scale)
Visual acuity in non-study eye same or better than study eye
Currently taking topical ocular hypotensive medication including a prostaglandin analogue
You may not be if
Aphakic eyes
Only one eye
History of, or current uveitis, Cystoid Macular Edema (CME) or cornea edema
Intraocular surgery or cornea/refractive surgery in study eye in past 6 months or anticipate need for eye surgery (including laser) in study eye during study period
Current retinal detachment
Uncontrolled infection in the eye
Clareo Health | Safety and Tolerability of a Prostaglandin Ocular Implant for Treatment of Open Angle Glaucoma
