Tuberculosis - Learning the Impact of Nutrition

Exclusion Criteria

• •In the team's judgement, individual is not expected to survive for 12 months
• •HIV infection or not willing to undergo HIV testing (if no documented HIV test)
• •Pregnant at enrollment
• •Known diabetes mellitus or evidence of diabetes on hemoglobin A1C (HA1C)
• •Xpert positive among those able to produce sputum
• •TB symptoms (night sweats, weight loss, cough) - Only if sputum positive
• •Any history of TB disease during their lifetime
• •We will retrospectively exclude household contacts of presumed TB cases whose cultures do not confirm Mtb or who are Xpert negative.
• •Evidence of kwashiorkor (pitting edema of foot or lower leg) those with BMI \<16
• •Abnormal K, Mg, Phos in those with BMI \<16
• •Pregnant at enrollment
• •No Xpert or culture confirmation and unable to provide sputum sample
• •No household contacts who share room
• •Known Multidrug-resistant tuberculosis (MDR-TB) or extensively drug-resistant tuberculosis (XDR-TB) case
• •BMI \<14 kg/m2
• •Abnormal K, Mg, Phos in those with BMI 14 - 16
• •Lower extremity edema/kwashiorkor those with BMI 14-16
• •Reported neuropathy in lower extremities (may result from thiamine deficiency)