A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients

Exclusion Criteria

• •Significant femoral or tibial deformity due to congenital or traumatic etiologies, inflammatory arthritis, post-septic arthritis, osteomyelitis, prior infection of knee joint, osteoporosis, dislocated or fragmented patella
• •Patients taking mast cell inhibitors and/or degranulation inhibitors for any reason.
• •The presence of infections, highly communicable diseases (e.g. AIDS), active tuberculosis, venereal disease, hepatitis.
• •Significant neurological or musculoskeletal disorders or disease that may adversely affect normal gait or weight bearing.
• •Presence of previous prosthetic knee replacement devices (of any type)
• •Metastatic disease
• •Psychiatric illness
• •Drug or alcohol abuse
• •Inability to participate in standard postoperative rehabilitation protocol