Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye Disease

Exclusion Criteria

• •1. Have any known hypersensitivity or contraindication to study treatments (including excipients), topical anesthetics or vital dyes.
• •2. Be unable to demonstrate correct instillation of over-the-counter (OTC) ocular lubricant.
• •3. Report discomfort in both eyes from instillation of OTC ocular lubricant during Visit 2 (based on score of ≥30 on the Drop Discomfort VAS).
• •4. Have used Restasis® (cyclosporine ophthalmic emulsion) within 30 days prior to Visit 1.
• •5. Have used Restasis® for more than 1 month (if prior use is reported).
• •6. Have used Xiidra® (lifitegrast ophthalmic solution) within 14 days prior to Visit 1.
• •7. Have had corneal graft surgery in either eye within 1 year.
• •8. Have recent or current evidence of ocular infection or inflammation in either eye.
• •9. Have current evidence of clinically significant blepharitis (defined as requiring lid hygiene therapy), conjunctivitis, or a history of herpes simplex or zoster keratitis in either eye.