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Efficacy of Low-level Laser Therapy, Hyaluronic Acid Gel and Herbal Gel as Adjunctive Tools in Gingivectomy Wound Healing-A Randomised Comparative Clinical and Histological Study
This study would be conducted to assess the effectiveness of low-level laser therapy, hyaluronic acid gel and herbal gel as adjunctive aids in the healing of gingivectomy wounds. As the gingivectomy wound heals by secondary intention, this study aims to compare the healing potential of low-level laser therapy, hyaluronic acid gel and herbal gel when applied topically at baseline, 1st day,3rd day and 7th day after gingivectomy procedure.
Low-level laser therapy applied to soft tissues stimulates specific metabolic processes in healing wounds. Major changes observed in wounds treated with low-level laser therapy(LLLT) include increased healthy granulation tissue formation with early epithelization, increased fibroblast proliferation and matrix synthesis. Hyaluronic acid is a polysaccharide gel and it has many properties that make it a potentially ideal molecule for assisting in wound healing by inducing early granulation tissue formation, inhibiting inflammation, providing epithelial turnover and also aiding in connective tissue angiogenesis. Hiora gel is a herbal astringent gel which helps in wound healing, reduces inflammation and also alleviates pain.
Age
18 - 35 years
Sex
ALL
Healthy Volunteers
Yes
Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre
Hyderabad, Telangana, India
Start Date
May 30, 2018
Primary Completion Date
October 15, 2018
Completion Date
October 30, 2018
Last Updated
November 6, 2018
30
ACTUAL participants
External bevel gingivectomy
PROCEDURE
Diode laser Biostimulation
DEVICE
Hyaluronic acid (Gengigel) topical application.
OTHER
Herbal gel (Hiora SG) topical application
OTHER
Lead Sponsor
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
NCT07169357
NCT07124143
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT04805463