Seven Versus Fourteen Days of Treatment in Uncomplicated Staphylococcus Aureus Bacteremia

Exclusion Criteria

• •Persistence of S. aureus bacteremia before randomization (S. aureus positive follow-up blood culture obtained 48-96 hours of the first positive blood culture)
• •Polymicrobial infection
• •Antibiotic treatment whit no antimicrobial activity to S. aureus administrated more than 12 hours of the first positive blood culture
• •Endocarditis or other intracardiac infection demonstrated with transthoracic or transesophageal echocardiography
• •Previous history of endocarditis
• •Pacemaker or other intracardiac implant
• •Failure to remove a likely focus of infection, such as central venous catheter within 72 hours of the first positive blood culture.
• •Prosthetics in joints and bones or vascular grafts
• •Pneumonia or infection involving bone or joints
• •Previously bone/join infection
• •S. aureus infection within the last 90 days
• •Pregnancy or breastfeeding
• •Neutropenia (blood neutrophils \< 1,0 x 109/l)
• •Untreated cancer
• •Chemotherapy within 90 days.