Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Northwestern University
Inpatients who will receive single daily doses of prednisone or methylprednisolone for treatment of their underlying condition and who become hyperglycemic will be eligible. Subjects will be randomized in a 1:1 fashion to one of two arms: (1) to their standard basal bolus insulin the addition of NPH insulin given at the time of the steroid adminstration, adjusting the dose based on the dose of steroid; (2) an increase in the basal and prandial bolus insulin doses based on the dose of steroid. Glycemic control and the incidence of hypoglycemia will be assessed over the first 3 days after initiating these insulin regimens.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients receiving once daily dosing of methylprednisolone or prednisone in a dose of 10 mg/day or greater
Hyperglycemic (Glucose level \> 126 mg/dL)
Diabetic and nondiabetic patients
Expected duration of hospital stay and time on steroids \>= 3 days
Patient of appropriate caregiver able to give Informed Consent
You may not be if
Patients with 2 or more doses of methylprednisolone/prednisone per day
Steroids other than methylprednisolone or prednisone
