Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Charite University, Berlin, Germany
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Existing health insurance, so that in case of random findings these can also be clarified
Patients with relapsed-remitting MS according to the MS diagnostic criteria according to McDonald 2010
Age 18-65
Consent ability and written consent
BMI between 19 and 45 kg / m2
EDSS \<4.5
Stable immunomodulatory therapy or no immunomodulatory therapy\> 6 months before confinement
In the last 2 years ≥ 1 relapse or within the last 2 years ≥ 1 new T2 lesions or ≥ 1 contrast-sensitive lesion in MRT
Consent that possible random findings are reported
You may not be if
Initiation or modification of immunomodulatory therapy during the study
Cortisone treatment in the last 30 days before enrollment
Relapse in the last 30 days before enrollment
Insulin-dependent diabetes mellitus (type I)
Intake of Omega 3 fatty acids (DHA, EPA) - more than 1 g / day
Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular system, respiratory tract, vascular system, brain, metabolism, thyroid) that could affect the course of the study
Malignant disease
Simultaneous participation in an interventional study or participation in an interventional study in the last two months before study inclusion
Clinically relevant addiction or substance abuse disorder (defined as alcohol, drug and drug abuse)
Nicotine consumption of \> 5 cigarettes per day and no willingness to stop consumption during therapeutic fasting.
Insufficient mental possibility of cooperation
Eating disorder
Kidney stones
Known metabolic disorders (e.g., fatty acid oxidation disorders, ketolysis / ketogenesis or glucogenesis disorder, hyperinsulinism (e.g., nesidioblastoma), pyruvate carboxylase deficiency)
Therapy with oral anticoagulants (e.g., Marcumar)
Pregnancy and breast feeding period
Suspected lack of compliance
Performing of a diet for weight reduction
Special diet for medical reasons
Change of the body weight of more than 5 kg within one month before the start of the Intervention
Medical, psychiatric or other conditions that restrict the patient's following abilities: to interpret the study information, to give informed consent, to adhere to the rules of the protocol, or to complete the study
Contraindications to MRT examinations \[persons with metallic implants (e.g., intracranial metal clips) and carriers of electronic devices (e.g., pacemaker) or persons with claustrophobia\]
Clareo Health | Nutritional Approaches in Multiple Sclerosis
