OCT in Diagnosis of Irregular Corneas

Inclusion Criteria

• •GROUP A:
• •Keratoconus:
• •1. CDVA ≥ 20/25 in the better eye; and both of the following in the worse eye
• •2. Topography characteristic of keratoconus or pellucid marginal degeneration
• •Contact lens-related corneal warpage:
• •1. Contact lens use; and
• •2. Topography irregularities
• •Dry eye:
• •1. Symptoms of dry eye documented by Ocular Surface Disease Index (OSDI) questionnaire score ≥ 30; and
• •2. Topography irregularities
• •3. Presence of punctate epithelial erosion on exam with surface staining
• •4. Aqueous deficiency or evaporative dry eye
• •Epithelial basement membrane dystrophy (EBMD):
• •1. Negative corneal fluorescein staining; and
• •2. Corneal opacities; and
• •3. Topography irregularities
• •Stromal addition or subtraction:
• •1. Scars; or
• •2. Salzmann's degeneration; or
• •3. Stromal dystrophies; or
• •4. Complication (visual complaints) after LASIK or photorefractive keratectomy (PRK)
• •Stromal distortion:
• •1. Radial keratectomy (RK); or
• •2. Corneal transplants.
• •Normal controls:
• •1. Healthy eyes with no previous eye procedures/surgeries.
• •GROUP B:
• •Participants will be selected from the keratoconus population in Group A based on topography findings.
• •GROUP C:
• •Participants will be selected from the stromal addition/subtraction and stromal distortion populations of Group A if they have vision primarily limited by scars, dystrophy, or high astigmatism that could benefit from PTK.