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Lead
Assiut University
Women aged between 18 and 60 years old with breast cancer and underwent mastectomy, ASA I or II were included in the study.
* Group I (lidocaine): Patients were received intravenous 1 mg/kg of 2 % lidocaine as a loading dose (just before induction of anesthesia) then received 2mg/kg /h lidocaine as maintenance dose (with maximum of 200 mg/h) till the end of the operation (skin closure).
* Group II (control):- A standardized equal volume of intravenous bolus dose of normal saline was given as loading dose then normal saline was administered on an equal rate of infusion.
Age
18–60
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Women aged between 18 and 60 years old with breast cancer and underwent mastectomy, American society of Anesthesiologist I or II
You may not be if
Patients with contralateral breast cancer, metastatic tumor, morbid obesity (BMI\> 40), allergy to an amide local anesthetic, or morphine sulphate, heart block, renal, or liver dysfunction, or substance abuse disorder, or chronic opioid use
Clareo Health | Serum Opiorphin Level After Intraoperative Intravenous Lidocaine Infusion
