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Analgesic Efficacy of Adding SCB With Low Concentration Bupivacaine Combined With Dexamethasone to ACB and Periarticular Injection on Postoperative Pain After TKA: Randomized Controlled Study
This study evaluate the efficacy of adding popliteal sciatic nerve block with low concentration bupivacaine and dexamethasone to abductor canal block for total knee arthroplasty in patient with NSAIDs prescribing precaution. Half of participants will receive popliteal sciatic nerve block, abductor canal block and periarticular injection, while the other half will receive a sham block, abductor canal block and periarticular injection.
After informed and consent, all patients will be devided into two groups, Sciatic group (group S) and Controlled group (group C). All patients will receive adductor canal block, then patients in group S will receive Sciatic nerve block with low concentration bupivacaine and dexamethasone while partients in group C will receive sham block. All patient will receive spinal anesthesia and intraoperative periarticular injection. Postoperative pain score, muscle strength, total morphine consumption and adverse events will be record in case record form.
Age
50 - 85 years
Sex
ALL
Healthy Volunteers
No
Siriraj Hospital, Mahidol University
Bangkoknoi, Bangkok, Thailand
Start Date
April 1, 2018
Primary Completion Date
February 1, 2019
Completion Date
February 1, 2019
Last Updated
April 3, 2018
50
ESTIMATED participants
bupivacaine and dexamethasone
DRUG
bupivacaine and lidocaine
DRUG
Ultrasound
DEVICE
Lead Sponsor
Mahidol University
NCT07456787
NCT06929871
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT07347821