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A Major Determinant Focused on the ECG or Echocardiogram for Pacing-induced Cardiomyopathy (PICM) and Its Clinical Outcome (PICM Syndrome) : Prospective, Multi-center, Observational Cohort Study.
Chronic right ventricular pacing has a deleterious effect on left ventricular (LV) function, namely pacing-induced cardiomyopathy (PICM). Several parametes make difference of effect on the occurrence of PICM and its subsequent clinical outcomes. In particular, recognition of a major determinant focused on the ECG or echocardiographic parameters including strain or genetic factor for occurrence of PICM may lead to better identification of patients at high risk. Investigators prospectively enroll a participant with documented high risk of PICM and clinically follow-up to idenify clinical impact of PICM (PICM syndrome) over a long period of time.
Investigators investigate a major determinant focused on the ECG or echocardiogram or genetic factor to predict the PICM after implantation of pacemaker. Not only QRS duration and mechanical strain but also genetic factor could be also investigated to predict the occurrence of PICM before diagnosis fo PICM
Age
20 - No limit years
Sex
ALL
Healthy Volunteers
No
Chung-Buk University Hospital
Chungju, South Korea
Chung-Nam University Hospital
Daejeon, South Korea
Chung-Ang University Hospital
Seoul, South Korea
Start Date
January 30, 2018
Primary Completion Date
February 28, 2027
Completion Date
February 28, 2028
Last Updated
October 2, 2025
1,000
ESTIMATED participants
Hyu Ryung Cho
CONTACT
Lead Sponsor
Eulji University Hospital
Collaborators
Data Source & Attribution
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