Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Eastern Finland
Ketamine-induced schizophrenia-like cognitive deficits in healthy volunteers are measured by using touchscreen-based cognitive tests. In addition, the study aims to assess whether ketamine-induced cognitive deficits detected by touchscreen-based cognitive tests are reversed by modafinil.
Age
20–40
Sex
MALE
Healthy volunteers
Accepted
You may be eligible if
Healthy Caucasian men aged 20-40 years
Body weight 50-100 kg
Body mass index 19-26 kg/cm2
Normal physical examination including heart rate (HR; 50-90/min) blood pressure (BP; diastolic 65-90 and systolic 110-140) normal haematological and clinical chemistry variables normal ECG as judged by the investigator
You may not be if
Visual disability or red-green color blindness
History of mental health disorders as determined by self-reported a) physician-determined diagnoses of mental health disorders, except for nicotine and caffeine dependence, or history of suicide attempt; b) medications for mental health disorders
History of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, or neurological disorder
History of orthostatic syncope
History of head injury with sequelae
First-degree relative with a history of psychosis or epilepsy/seizure disorder or of a condition with risk of seizures
Current regular medication
Vaccination 2 weeks prior to study or during the study
Known or suspected allergy/hypersensitivity to any drug
History of regular alcohol consumption
Current substance dependence (excluding nicotine and caffeine).
Use of tobacco- or nicotine-containing products in excess of the equivalent of 5 cigarettes per day
Use of any medication or alcohol 24 hours before each study visit
Education less than high school
Clinically relevant symptoms of depression, anxiety or sleep disturbances
Donation of blood within 1 month prior to study
Participation in any study with an investigational product within 2 months prior to study
Clinical signs of suicidal or violent behaviour or psychotic symptoms
Clareo Health | Touchscreen-based Cognitive Tests in Healthy Volunteers
