Touchscreen-based Cognitive Tests in Healthy Volunteers

Exclusion Criteria

• •Visual disability or red-green color blindness
• •History of mental health disorders as determined by self-reported a) physician-determined diagnoses of mental health disorders, except for nicotine and caffeine dependence, or history of suicide attempt; b) medications for mental health disorders
• •History of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, or neurological disorder
• •History of orthostatic syncope
• •History of head injury with sequelae
• •First-degree relative with a history of psychosis or epilepsy/seizure disorder or of a condition with risk of seizures
• •Current regular medication
• •Vaccination 2 weeks prior to study or during the study
• •Known or suspected allergy/hypersensitivity to any drug
• •History of regular alcohol consumption
• •Current substance dependence (excluding nicotine and caffeine).
• •Use of tobacco- or nicotine-containing products in excess of the equivalent of 5 cigarettes per day
• •Use of any medication or alcohol 24 hours before each study visit
• •Education less than high school
• •Clinically relevant symptoms of depression, anxiety or sleep disturbances
• •Donation of blood within 1 month prior to study
• •Participation in any study with an investigational product within 2 months prior to study
• •Clinical signs of suicidal or violent behaviour or psychotic symptoms