Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Colorado, Denver
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
individuals ≥ 18 years of age with severe heart failure (HF) and who have been approved by the advanced HF selection committee for LVAD implantation.
You may not be if
Patients with pre-existing right ventricular (RV) dysfunction/failure, defined as:
1. Imaging evidence of moderate-severe RV dysfunction on echocardiography
2. Hemodynamic evidence of RV dysfunction with:
* a right-atrial pressure (RAP): pulmonary capillary wedge pressure (PCWP) ratio of ≥ 0.67 (note: this index compares pressures on the right \[RAP\] and left \[PCWP\] side of the heart;
* an RAP/PCWP ratio ≥ 0.67 provides hemodynamic evidence of RV dysfunction.
3. Clinical evidence of preexisting RV dysfunction, as indicated by significant (3-4+ peripheral edema) and/or elevated jugular venous pressures on clinical examination.
4. Patients with end-stage renal disease requiring hemodialysis
5. Patients requiring temporary hemodynamic support prior to LVAD implantation with temporary LVADs, and/or veno-arterial extracorporeal membrane oxygenators ("ECMO").
6. Planned concurrent implantation of right ventricular assist device
