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TERMINATEDPhase 2NCT03430544

Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder

This is a phase II, randomized, single-blind, placebo-controlled study to examine whether cariprazine (1.5 or 3 mg/d) 1) alters brain and/or behavioral responses to probes of reward and inhibition and...

Lead sponsor: Anna Rose Childress, Ph.D.•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Anna Rose Childress, Ph.D.

Collaborators

National Institute on Drug Abuse (NIDA)

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. An informed consent voluntarily signed and dated by the subject.
•2. Physically healthy males and females with cocaine use disorder.
•3. Ability to read at or above eighth grade level and speak, understand, and write in English.
•4. Willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures.
•5. Available for an inpatient stay, when applicable.

Exclusion Criteria

•1. Certain psychological disorders that could put subjects at risk during participation in the study.
•2. Certain lifetime or current medical disorders or conditions that could put subjects at risk during participation in the study.
•3. Medical contraindications for MRI, when applicable.
•4. Has received medication that could interact adversely with cariprazine within the time of administration of study agent based on the study physician's guidance.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 9, 2020Terms

Trial snapshot

StatusTERMINATED

PhasePHASE2

Enrollment14

Start dateApr 2018

Last updatedSep 9, 2020

Condition

Cocaine Use Disorder

Locations shown

University of Pennsylvania

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 9, 2020Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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