A confirmed diagnosis of moderate to very severe AECOPD
Age between 40 and 80 years
Syndrome differentiation meets criteria of syndrome of external cold and internal fluid,syndrome of phlegm-heat congesting lung,or syndrome of phlegm-damp amassing in lung
Without participations in other interventional trials in the previous one month
With the informed consent signed
You may not be if
Pregnant and lactating women
Dementia, mental disorders and reluctant partners
Complicated with heart failure (NYHA Class IV), or Serious cardiac arrhythmias, or unstable hemodynamics
Current respiratory disorders other than COPD (e.g., bronchiectasis, active tuberculosis, pneumothorax, Pleural effusion, pulmonary thromboembolic, or Neuromuscular diseases affect respiratory movement function)
Combined tumor
Treated outside the hospital for more than 7 days
Need to carry out invasive mechanical ventilation respiratory failure
Complicated with serious hepatic and renal diseases (liver cirrhosis, portal hypertension, bleeding of varicose veins, dialysis, or renal transplantation)