The Affiliated Hospital of Xuzhou Medical University
With
The First People's Hospital of Xuzhou
This study aims to explore the best effective dose and adverse reaction of febuxostat in lowering serum uric acid to low level in patients with Chronic Renal Disease at different stages. To elucidate that low levels of serum uric acid can delay the progression of renal damage. Promote the application of anti uric acid drugs in the treatment of chronic renal failure and delay the progress of CKD in patients
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Non-dialysis CKD patients with serum uric acid greater than 7mg/dl.
eGFR≥15ml/min/1.73m².
Low salt, low protein, low purine diet.
You may not be if
Take drugs that raise blood uric acid at the same time.
Patients with gout attacks.
Patients with pregnant, lactating.
Autosomal dominant polycystic kidney disease.
Patients with poor general condition and multiple organ failure.
Clareo Health | Effect of Hyperuricaemia on Chronic Renal Disease
