ViBone in Cervical and Lumbar Spine Fusion

Exclusion Criteria

• •Long term use of medications that are known to inhibit fusion or bone metabolism or immune suppressants 6 months prior to surgery (i.e., steroids, chemotherapy, DMARDs, etc.)
• •Treatment with radiotherapy
• •Acute or chronic systemic or localized spinal infections
• •Instability associated with major reconstructive surgery for primary tumors or metastatic malignant tumors of the cervical (for ACDF patients) or lumbar (for TLIF, PLIF, ALIF, or LLIF patients) spine
• •Previous pseudoarthrosis at any level of the cervical (for ACDF patients) or lumbar (for
• •TLIF, PLIF, ALIF, or LLIF patients) spine
• •Nursing mothers or women who are pregnant or plan to become pregnant during the course of the study
• •Current or recent history of malignancy or infectious disease. Patients with current or recent history of basal cell carcinoma are eligible.
• •Inability to provide informed consent
• •Rapid joint disease, bone absorption, osteomalacia, and/or diagnosed osteoporosis (bone density score of ≤-2.5).
• •Other medical or surgical conditions which would preclude the potential benefit of surgery, such as congenital abnormalities, immunosuppressive disease, elevation of sedimentation rate unexplained by other diseases, elevation of white blood count (WBC), or marked left shift in the WBC differential count.
• •Active local or systemic infection or is undergoing adjunctive treatment for local or systemic infection.