PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery.

Exclusion Criteria

• •Cesarean delivery before fetal viability (24 0/7 weeks gestational age)
• •Unplanned Cesarean delivery
• •Intrauterine fetal demise
• •Known allergic reactions to components of the PICO NPWT system
• •Systemic bacterial or fungal infection at the time of surgery
• •Diagnosis of systemic or remote-site skin infections at time of delivery
• •Treatment with another investigational drug or other intervention within 7 days prior to cesarean delivery or 42 +/- 10 days after cesarean delivery
• •Delivery for suspected intrauterine infection (defined as maternal fever plus one clinical criteria)
• •Critical illness or immune-compromising disease (eg acquired immunodeficiency syndrome)
• •Chronic steroid use
• •Pre-operatively assessed to have a CDC Wound Classification of:
• •Class III (Contaminated): Open, fresh, accidental wounds, and/or major breaks in sterile technique or gross spillage from the gastrointestinal tract
• •OR - Class IV (Dirty-Infected): Old traumatic wounds with retained devitalized tissue and those that involve existing clinical infection or perforated viscera
• •High-risk for anesthesia (American Society of Anesthesiologists \[ASA\] class P4 - P6)
• •Intra-operative hemorrhage requiring blood transfusion, disseminated-intravascular coagulopathy (DIC) or any other medical or surgical condition during the Cesarean section deemed by the investigator to pose a prohibitively high risk for surgical re-exploration
• •Unable to speak or understand English, with no interpreter available.