Novel INXN-4001 Triple Effector Plasmid in Heart Failure

Exclusion Criteria

• •Women who are pregnant or nursing
• •Patients who have been on another clinical trial for heart failure in the last 90 days, or have received any stem cell or gene therapy within the previous year.
• •Patient is not able to complete a Six Minute Walk Test or unable to tolerate an LVAD wean in the past 3 months
• •Patient has an active infection requiring systemic antibiotics or an autoimmune disease requiring systemic immunosuppressants
• •Patient has a history of arrhythmia, uncontrolled diabetes, diabetic retinopathy, systemic lupus erythematosus, macular degeneration, hyper-coagulation, or stroke
• •Patient has had a myocardial infarction related to ischemia within the past 30 days
• •Patient has had certain prior surgeries such as organ transplant, cardiac transplantation, left ventricle reduction surgery, or cardiomyoplasty
• •Patient has infectious disease, such as hepatitis B or C, or human immunodeficiency virus (HIV)
• •Patient has a history of cancer within the past 3 years