Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hasselt University
With
Jessa Hospital
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Diagnosed with non-invasive (stage 0) or invasive (stage 1, 2 and 3A) breast adenocarcinoma
Age 18 years or above
Are planned to undergo at least 3 cycles of taxane treatment (i.e. paclitaxel or docetaxel)
Have no documented or observable psychiatric or neurological disorders that might interfere with study participation (e.g., dementia or psychosis).
Signed informed consent
You may not be if
Have a history of neuropathy before taxane treatment due to other medical conditions: diabetes, peripheral vascular disease, HIV infection, significant degenerative or familial neurologic disorder, nerve compression injuries (i.e., carpal tunnel syndrome, brachial plexopathy, spinal stenosis, or spinal nerve root compression)
Taking stable doses of medication on prescription or dietary supplements for peripheral neuropathy. Related medications are: gabapentin, pregabalin, nortriptyline, amitriptyline, duloxetine, venlafaxine; lidocaine, opioid tramadol and other narcotics; NSAIDs; glutamine, glutathione, vitamin E and vitamin B12; Patients need to agree not to initiate a new therapy two weeks before and during the study period.
Metastatic disease
Have a diagnosis of ethanol addiction or dependence within the past 10 years.
Concurrent chemotherapy with neurotoxic chemotherapeutic agents (i.e. platinum compounds or vinca alcaloids)
Severe or unstable cardio- respiratory or musculoskeletal disease
