Diagnosis of ALS according to the El Escorial criteria.
Age 18 years to 80 years old
Disease duration less than 36 months
Patients logistically able to attend and be evaluated at baseline, 3 and 6 months
You may not be if
Patients with diabetes mellitus
Patients with glaucoma, refractive errors of ± 6 diopters or more, or other ophthalmologic disorders such as media opacities that could interfere with retinal OCT assessment
