Finding studies
Finding studies
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Lead
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
With
Primary Objective: 1\) To determine if CPI-613 increases overall survival (OS) when used in combination with mFOLFIRINOX, in patients with locally advanced pancreatic cancer. Secondary (Exploratory) Objectives: 1. To assess the safety of CPI-613 + mFOLFIRINOX combination in patients with locally advanced pancreatic cancer. 2. To collect tissue specimens for future correlative studies 3. To estimate median progression free survival (PFS) when CPI- 613 is used in combination with mFOLFIRINOX, in patients with locally advanced pancreatic cancer. 4. To estimate the percent resected when CPI-613 is used in combination with mFOLFIRINOX in patients with locally advanced pancreatic cancer
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted