Imaging Tau in Alzheimer's Disease and Normal Aging

Exclusion Criteria

• •1. Past or present history of certain brain disorders other than MCI or AD.
• •2. Certain significant medical conditions, which make study procedures of the current study unsafe. Such serious medical conditions include uncontrolled epilepsy and multiple serious injuries.
• •3. Contraindication to magnetic resonance imaging (MRI) scanning.
• •4. Conditions precluding entry into the scanners (e.g. morbid obesity, claustrophobia, etc.).
• •5. History of kidney disease or presence of impaired kidney function based on laboratory tests at screening visit.
• •6. History of liver disease or presence of impaired liver function based on laboratory tests at screening visit.
• •7. Participation in the last year in a clinical trial for a disease modifying drug for AD.
• •8. Inability to have a catheter in subject's vein for the injection of radioligand.
• •9. Inability to have blood drawn from subject's veins.